Mercredi, Septembre 08, 2010
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Prix pour les meilleures présentations

ssc_2010_prix

Félicitations!

Le 97ème congrès annuel de la Société Suisse de Chirurgie s'est terminé à Interlaken le 28 mai. La participation a été extrêmement élevée et la qualité des présentations remarquée.

Dans ce contexte, félicitations au Dr Christian Toso, Dr Pascal Gervaz et au Dr Francesco Volonté qui ont reçu des prix scientifiques pour leurs exposés.

 

 

 

 

 

97e congrès annuel de la Société Suisse de Chirurgie
8e congrès annuel en commun avec la Société Suisse de Chirurgie Thoracique et Cardio-Vasculaire


Le Dr Christian Toso, médecin adjoint dans le Service de Chirurgie Viscérale et Transplantation, a remporté le prix de la Société Suisse de Chirurgie pour la recherche clinique grâce à son travail intitulé "Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma", qui a depuis été publié dans Hepatology,2010 Apr;51(4):1237-43.

Voici l'abstract:

Liver transplantation is an important treatment option for selected patients with nonresectable hepatocellular carcinoma (HCC). Several reports have suggested a lower risk of posttransplant tumor recurrence with the use of sirolimus and a higher one with calcineurin inhibitors, but the selection of an ideal immunosuppression protocol is still a matter of debate. The aim of this study was to define the immunosuppression associated with the best survival after liver transplantation for HCC. It was based on the Scientific Registry of Transplant Recipients and included 2,491 adult recipients of isolated liver transplantation for HCC and 12,167 for non-HCC diagnoses between March 2002 and March 2009. All patients remained on stable maintenance immunosuppression protocols for at least 6 months posttransplant. In a multivariate analysis, only anti-CD25 antibody induction and sirolimus-based maintenance therapy were associated with improved survivals after transplantation for HCC (hazard ratio [HR] 0.64, 95% confidence interval [CI]: 0.45-0.9, P < or = 0.01; HR 0.53, 95% CI: 0.31-0.92, P < or = 0.05, respectively). The other studied drugs, including calcineurin inhibitors, did not demonstrate a significant impact. In an effort to understand whether the observed effects were due to a direct impact of the drug on tumor or more on liver transplant in general, we conducted a similar analysis on non-HCC patients. Although anti-CD25 induction was again associated with a trend toward improved survival, sirolimus showed a trend toward lower rates of survival in non-HCC recipients, confirming the specificity of its beneficial impact to cancer patients. Conclusion: According to these data, sirolimus-based immunosuppression has unique posttransplant effects on HCC patients that lead to improved survival.


 

 

Le Dr Pascal Gervaz, médecin adjoint dans le Service de Chirurgie Viscérale et Transplantation, a remporté le "Prix Forum recherche clinique" en raison de ses travaux sur les abords par laparoscopie ou laparotomie pour maladie diverticulaire. Son travail a été aussi publié sur Annals of Surgery:
Gervaz P, Inan I, Perneger T, Schiffer E, Morel P. A "Prospective, Randomized, Single-Blind Comparison of Laparoscopic Versus Open Sigmoid Colectomy for Diverticulitis". Ann Surg. 2010 May 25.

Voilà l'abstract:

OBJECTIVE:: The aim of this study was to compare open and laparoscopic sigmoid resection for diverticulitis with the patient and the nursing staff blinded to the surgical approach. METHODS:: A total of 113 patients scheduled for an elective sigmoidectomy were randomized to receive either a conventional open (54 patients) or a laparoscopic (59 patients) approach. Postoperatively, an opaque wound dressing was applied and left in place for 4 days, and patients from both groups were managed similarly. The primary endpoints for analysis were (1) postoperative pain; (2) duration of postoperative ileus; and (3) duration of hospital stay (ClinicalTrials.gov, number NCT 00453830). RESULTS:: The median duration of procedure was 165 minutes (range, 90-285) in the laparoscopy group and 110 minutes (range, 70-210) in the open group (P < 0.0001). The median delay between surgery and first bowel movement was 76 (range, 31-163) hours in the laparoscopy group versus 105 (range, 53-175) hours in the open group (P < 0.0001). The median score for maximal pain (assessed by a visual analog scale) was 4 (range, 1-10) in the laparoscopy group and 5 (range, 1-10) in the open group (P = 0.05). Finally, the median duration of hospital stay was 5 days (range, 4-69) in the laparoscopy group versus 7 days (range, 5-17) in the open group (P < 0.0001). CONCLUSION:: Laparoscopic sigmoid resection is associated with a 30% reduction in duration of postoperative ileus and hospital stay; by comparison, benefits in terms of postoperative pain appear less impressive, when the patient is blinded to the surgical technique.

 

 

Le Dr Francesco Volonté, chef de clinique dans le Service de Chirurgie Viscérale et Transplantation, à remporté le prix pour la meilleure présentation vidéo en raison de son travail sur la réalité augmentée en salle d'opération.

Voilà le résumé de la vidéo, que vous trouverez dans son intégralité au dessous:

F.Volonte, P.Bucher, F.Pugin, A.Carecchio, M.Sugimoto, O.Ratib, P.Morel "Mixed reality for laparoscopic distal pancreatic resection"

Laparoscopic distal pancreatectomy may be a challenging procedure because of the inability for the surgeon to touch structures hidden in the pancreatic tissue. Moreover, the anatomy of the area requires extra care because a major local bleeding would quickly perturb the laparoscopic technique. We brought in the operating room a new tool that increased perception of the surgeon in the operative field superimposing 3D images obtained from simple CT scan with a beamer.
Our patient had a small nodule in the tail of the pancreas with a PET CT hot spot on the surface of the right colon, not visible at colonoscopy, possibly a tumor implant. For a precise localization, the two lesions were plotted (Osirix) with different colors on the CT images and therefore safely isolated on 3D reconstructions. These images were then projected on the patient himself with a beamer fixed to the operating table. This technique of augmented reality enabled us to accurately locate anatomical landmarks on the surface of the patient and plan the lesions resection. The instruments have been placed with greater reliability knowing exactly where the lesions were located. The 3D image was also displayed on a large screen positioned at the left of the surgeon.
The nodule on the surface of the right flank was resected in the middle of the fatty tissue overlying the colon thanks to the directives given by the superposition of reconstructed images. The frozen section confirmed the presence of a fibrous and inflammatory response without signs of malignancy. The pancreatic nodule clearly identified and resected. The splenic vessels spared because of their easier spatial identification.

The overlay of virtual images on the real world is a valuable aid in laparoscopic and robotic interventions. These techniques remove the operator from the operating field, by interposing a mechanical instrument or a digital interface between the patient and the surgeon. Overlaying 3D images on the patient himself in order to accurately locate structures and displaying the same images beside the laparoscopic video gives the surgeon a new perception of the operating field and a real advantage compared to simple laparoscopy. This technique substitute to the lack of sense of touch that is proper to the laparoscopic technique.

 

 

 

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